Cambiamenti nello stato di salute e risultati clinici a lungo termine nei pazienti con fibrillazione atriale.

IMPORTANCE: Improving health status, including symptoms and quality of life, is a key goal in the management of atrial fibrillation (AF). However, whether improvements in patient-reported health status are associated with subsequent clinical outcomes remains unclear. OBJECTIVE: To evaluate the association between changes in health status and long-term adverse clinical outcomes in patients with AF. DESIGN, SETTING, AND PARTICIPANTS: This cohort study used data from a prospective multicenter registry in Japan that enrolled patients aged 22 to 94 years with newly diagnosed AF or who were newly referred for AF management between September 20, 2012, and May 22, 2018. The registry collected foll