Valore prognostico della funzione atriale sinistra nell'amiloidosi cardiaca: una revisione sistematica e meta-analisi.

To evaluate the prognostic value of left atrial (LA) function parameters, assessed by echocardiography or cardiac magnetic resonance, in patients with cardiac amyloidosis. We conducted a systematic review and meta-analysis of cohort studies evaluating the prognostic role of LA function parameters, such as left atrial reservoir strain (LASr), in confirmed light-chain amyloid cardiomyopathy (AL-CM) or transthyretin amyloid cardiomyopathy (ATTR-CM). Twenty studies were included, comprising a total of 3,260 participants. LASr was inversely associated with all-cause mortality (HR: 0.92; 95% CI: 0.88-0.96), although with low certainty of evidence. LASr was also associated with a lower risk of atri