Gravità dell'attività MASH rilevata tramite RMI corretta per l'ironio predice la resistenza all'insulina e il rischio cardiometabolico nel diabete di tipo 2.

CONTEXT: Multiparametric magnetic resonance iron-corrected T1 mapping (cT1) may help identification and risk-stratification of steatohepatitis (MASH). OBJECTIVE: In type 2 diabetes, metabolic dysfunction-associated steatotic liver disease frequently advances to steatohepatitis with significant fibrosis and increased risk of developing cirrhosis. cT1 allows MASH risk-stratification by measuring liver disease activity (fibro-inflammation) but its association with cardiometabolic risk factors that drive liver disease progression in T2D (insulin resistance, lipotoxicity, and metabolic syndrome) remains unclear. METHODS: We recruited 109 participants with T2D from primary care settings who were