Esiti cardiometabolici dopo la remissione chirurgica dell'iperortosilismo endogeno: uno studio di cohorte prospettico.

CONTEXT: Evidence on the evolution of cardiometabolic comorbidities following surgical remission of hypercortisolism is scarce. OBJECTIVE: To determine the impact of surgical remission on cardiometabolic comorbidities in patients with endogenous hypercortisolism and to identify factors associated with cardiometabolic improvement. METHODS: Prospective single-center cohort study (2019-2025) of adults with Cushing syndrome (CS) or mild autonomous cortisol secretion (MACS) with surgical remission of hypercortisolism. Outcomes included (1) changes in severity of hypertension, diabetes mellitus (DM), hyperlipidemia, and obesity between baseline, 3, and 12 months postremission and (2) factors ass