Esiti clinici off-pump confrontati con la chirurgia di bypass delle arterie coronarie con pompaggio in on-paziente in pazienti diabetici: revisione sistematica aggiornata e meta-analisi.

BACKGROUND: Patients with diabetes mellitus are at high risk for coronary artery disease and frequently undergo coronary artery bypass grafting (CABG). Off-pump CABG (OPCAB) has been proposed to reduce perioperative complications compared with on-pump CABG (ONCAB), but long-term outcomes remain uncertain. METHODS: We conducted a systematic review and meta-analysis in accordance with PRISMA 2020 and Cochrane guidelines. Five databases were searched through May 2025 for randomized trials and observational cohorts comparing OPCAB and ONCAB in adults with diabetes. Risk of bias was assessed using RoB-2 and ROBINS-I, and evidence quality was graded with GRADE. RESULTS: Seventeen studies were in