Associazione di epinefrina e esito in arresto cardiaco con ritmo shockabile refrattario: un'analisi basata sulla popolazione con match di punteggio di propensione.

BACKGROUND: Epinephrine use in cardiac arrest is increasingly controversial, with contrasting results according to initial rhythm. We assessed the association between epinephrine use and favorable neurological outcome among patients with out of hospital cardiac arrest with refractory shockable arrest. METHODS: In this multicentric population-based prospective registry, we included all patients with out-of-hospital cardiac arrest, with persistent ventricular fibrillation after at least 3 defibrillations from 15/05/2011 to 31/12/2021 in Paris and its suburbs. Primary outcome was survival with a favorable neurological outcome (Cerebral Performance Categories level 1 or 2 at hospital discharge)