Vasospasmi coronarici e altre manifestazioni cardiache nella granulomatosis eosinofila con poliangiite: impatto clinico e frequenza in uno studio monocentrico su 103 pazienti.

BACKGROUND: Eosinophilic granulomatosis with polyangiitis (EGPA) is a systemic necrotising vasculitis characterised by tissue and blood hypereosinophilia. Cardiac involvement has previously been identified as the most significant predictor of mortality. OBJECTIVE: To identify and characterise previously untreated patients with EGPA and their cardiac manifestations at disease onset. METHODS: A retrospective monocentre study was conducted on 103 patients. Upon patient presentation, detailed multidisciplinary physical evaluations and laboratory diagnostics were performed. Cardiac events were defined as EGPA-related abnormalities in ECG, echocardiography, cardiac MRI, invasive coronary angiogr