Rianimazione guidata dalla fisiologia.

Current cardiopulmonary resuscitation (CPR) guidelines rely on standardized metrics, yet substantial evidence reveals significant variability in patients' physiologic responses. Physiology-directed CPR represents an innovative approach aimed at improving cardiac arrest outcomes by tailoring resuscitation efforts to patient-specific physiologic responses rather than rescuer performance alone. Data indicate that intra-arrest markers including arterial blood pressure, end-tidal carbon dioxide, and cerebral oximetry are associated with cardiac arrest outcomes and can potentially be targeted during CPR. This article explores the underlying physiology, supporting data, advantages, and limitations