Cura respiratoria dei neonati nati ai limiti di vitalità: un approccio fisiologico e di sviluppo dalla nascita alla dimissione ospedaliera presso l'Università dell'Iowa.

The authors present the University of Iowa's approach to respiratory management for infants born at 21 to 24 weeks' gestation in 3 phases of care. In the acute phase, they address the challenges of supporting immature lungs in the canalicular stage by using early high-frequency jet ventilation to minimize volutrauma with careful avoidance of hyperinflation. In the subacute phase, ventilatory support continues until there are consistent signs of respiratory and developmental readiness for extubation, followed by the postextubation weaning phase of noninvasive support. This approach prioritizes lung protection and growth, and minimizes long-term morbidity in extremely low gestational age infan