Carico del virus respiratorio sinciziale e dell'influenza negli adulti - uno studio di cohorte nazionale danese.

OBJECTIVES: Like influenza, respiratory syncytial virus (RSV) is a common cause of severe acute respiratory infection (ARI) in adults. With RSV vaccines recently approved, data on the burden of disease are required. Our objective was to investigate the short- and long-term clinical and economic burden of ARI in Danish adults over the past decade, with a primary focus on RSV, contextualising with influenza. METHODS: A nationwide cohort study in Denmark, including adults ≥18-year-old recorded with an ARI from 1 July 2011 to 30 June 2022 (i.e. exposed), matched 1:3 with individuals without ARI (unexposed). We assessed adverse clinical outcomes, direct and indirect healthcare resource utilizati