Frailty e malattia coronarica: patofisiologia proposta e complesso interazione influenzante la gestione e gli esiti negli adulti anziani.

Coronary artery disease (CAD) and frailty frequently coexist in older adults and represent a growing clinical challenge in the context of an ageing population. Frailty, a multidimensional syndrome characterised by reduced physiological reserve and increased vulnerability to stressors, is highly prevalent among older patients with CAD and is associated with adverse outcomes. This review examines the complex interplay between frailty and CAD, highlighting shared pathophysiological mechanisms, and further explores the impact of frailty on clinical presentation, risk stratification and therapeutic decision-making in CAD. A range of frailty assessment tools are discussed, although no single tool