Impatto dell'immunizzazione del virus respiratorio sinciziale sulla percentuale di otite media acuta pediatrica: un'analisi in serie temporale.

BACKGROUND: Acute otitis media (AOM) is the leading cause of antibiotic prescription in children. Respiratory syncytial virus (RSV) is suspected to play an important role in AOM. The aim of this study was to estimate the impact of RSV immunization on the rate of subsequent AOM in children, as this effect remains unknown. METHODS: We conducted an interrupted time-series analysis based on a French network involving 110 ambulatory pediatricians, trained in pediatric infectious diseases (PARI network). All ambulatory visits for AOM, from June 2017 to February 2025 were included. The main outcome was the monthly rate of pediatric ambulatory visits for AOM in infants aged < 12 months per 1000 ped