Fattori che influenzano la delirium postoperatorio nei pazienti con malformazioni cardiache congenite: una revisione sistematica e meta-analisi.

PROBLEM: Postoperative delirium (POD) is multifactorial and seriously affects prognosis and long-term quality of life in children with congenital heart disease (CHD). In this review, we synthesized evidence on influencing factors for POD in CHD to guide clinical identification and intervention. METHODS: We conducted a systematic search of nine databases to identify studies on POD risk factors in CHD. To conduct the meta-analysis, we used fixed-effects and inverse-variance heterogeneity models in STATS 18.0. RESULTS: This meta-analysis included 12 papers comprising 3169 participants. Narrative synthesis suggested that surgical complexity, pain, benzodiazepines, opioids, and aortic cross-cla