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Review

L'obesità e il fallimento cardiaco con eiezione ridotta: una revisione.

Khan MS, Javaid SS, Petrie MC, Zieroth S, Anker SD, Butler J, et al.

Journal of the American College of Cardiology·1 giugno 2026·DOI ↗

Obesity and heart failure with reduced ejection fraction (HFrEF) frequently coexist. In fact, most patients with HFrEF are overweight or have concomitant obesity. However, despite this high prevalence, obesity in HFrEF has received limited attention as most recent reviews have concentrated on heart failure broadly or on the heart failure with preserved ejection fraction (HFpEF) phenotype. This limited attention may, in part, be attributed to the stronger and more consistent pathophysiological and epidemiologic associations observed between obesity and HFpEF, whereas the relationship between obesity and HFrEF remains less well characterized. Much of this uncertainty reflects inconsistent find

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