Efficacia e sicurezza comparative delle modalità di energia per l'ablazione catetere per l'aritmia atriale: una meta-analisi di rete dei trial randomizzati.

BACKGROUND: Pulsed field ablation (PFA) has reshaped the atrial fibrillation (AF) ablation landscape, yet the relative advantages and limitations of currently available catheter ablation energy modalities-radiofrequency ablation (RFA), cryoballoon ablation (CBA), laser balloon ablation, PFA, and lattice-tip dual-energy ablation-remain incompletely understood. OBJECTIVE: This study aimed to compare the efficacy, procedural efficiency, and safety of catheter ablation modalities for AF. METHODS: MEDLINE, Scopus, and the Cochrane Library were searched through March 15, 2026. Comparative effects across 5 ablation energy modalities were synthesized using random-effects network meta-analysis. RE